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The mechanism of action is very imbalanced, since while it has a comparable GIP receptor binding affinity to native GIP, the affinity to the native GLP-1 receptor is five times lower [20, 21]

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Besides these metabolic effects, GLP-1 drugs also appear to have an impact on brain health and mental health

HSBC has projected that orforglipron will generate close to $10 billion in peak-year sales, according to Morningstar
