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The standard semaglutide protocol increases the dose every 4 weeks, but some patients benefit from staying at a lower dose for 68 weeks before advancing

Dipeptidyl peptidase-4 inhibitors and cardiovascular outcomes: meta-analysis of randomized clinical trials with 55,141 participants

Others remain cautious due to limited long-term utilization data and the likelihood that discontinuing medication may lead to weight regain

Report any suspected side effects to your healthcare provider and consider reporting them through the MHRA's Yellow Card scheme (yellowcard.mhra.gov.uk), including during pregnancy or breastfeeding