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It is important to note that an impact of the Inflation Reduction Act is that small molecule therapeutics may continue to be deprioritized in favor of biologics, so development of oral biologics may (unfortunately) be more compelling for companies in this context

Many of the states that do cover GLP-1s for obesity under Medicaid have body mass index requirements and other criteria patients must meet before the drugs are covered, according to a report by the actuarial firm Milliman

That means that for every 1,000 patients with a first-time GLP-1 prescription, 11 were diagnosed with sleep apnea within 15 days in 2024, up from 8 in 2020

Saxenda is sometimes prescribed off-label for metabolic dysfunction-associated steatohepatitis (MASH)