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The National Cancer Institute (NCI) defines cancer disparities as adverse differences in cancer-related measures, such as number of new cases, number of deaths, cancer-related health complications, survivorship and quality of life after cancer treatment, screening rates, and cancer stage at diagnosis, that exist among certain population groups (see Sidebar 2 )

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The 8.3 percentage point efficacy advantage for retatrutide is meaningful21 pounds difference for a 250-pound person

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Nature, 542 (7640), 177185