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Problems in GLP-1RA development Cost-effective and reliable trial endpoints for MASLD medication Assessing long-term liver benefits in clinical trials has remained a complex issue

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, Glucagon-Like Peptide-1 Regulates the Proopiomelanocortin Neurons of the Arcuate Nucleus Both Directly and Indirectly via Presynaptic Action, Neuroendocrinology 111, no

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10.3390/nu17081303 [DOI] [PMC free article] [PubMed] [Google Scholar] Granata A, Maccarrone R, Anzaldi M, Leonardi G, Pesce F, Amico F, et al (2022) GLP-1 receptor agonists and renal outcomes in patients with diabetes mellitus type 2 and diabetic kidney disease: State of the art