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Nature 521 (7552), 322327

This occurs through two main pathways: (1) FXR induces a small heterodimer partner that represses CYP7A1 and CYP8B1 by inhibiting hepatocyte nuclear factor 4 and liver receptor homolog 1

While its still early in human research, the pathways it targets are well-documented in metabolic science, and the results so far are promising