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Supports healthy blood pressure: A 2022 research review found that berberine lowered systolic blood pressure (the top number, which measures pressure when the heart pumps), by an average of 5.46 mmHg

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GIP Receptor: Enhances insulin release in response to meals and promotes fat metabolism, amplifying weight loss and improving lipid profiles

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However, a pooled analysis of liraglutide trials demonstrated that blood pressure lowering occurs within two weeks of treatment initiation, suggesting other effects on vasculature beyond weight loss [36]