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Some studies have found that these side effects are most common during the first eight to 12 weeks of treatment

In a recent publication, it has been found that decreased prevalence of genus Adlercreutzia is associated with impaired barrier function in healthy relatives of CD patients [38]

Long-term application of GLP-1RAs may also elevate the release of endogenous GLP-2, which is a cell-specific growth hormone regulating the growth of the small intestine, colonic villi and crypts, increasing the length and weight of the small intestine, and reducing antral motility
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It also reduces inflammation and improves insulin sensitivity, enhancing the bodys response to insulin, promoting glucose uptake into cells, as well as reducing the risk of associated metabolic complications
