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2.6 Sensitivity analysis and price threshold analysis We performed a univariate sensitivity analysis to evaluate the impact of changing key inputs in the model, including the discount rate, initial utility, time horizon, costs, and disutility scores (Supplementary Table S5)

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The roles of peripheral 5-HT are diverse, but it primarily regulates gut motility and plays a role in hemodynamics and vasoconstriction [20]

In patients who have undergone gastric sleeve surgery, the physiological landscape is already altered in ways that overlap with semaglutide's effects