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It is postulated that GLP-1 RAs activate the GLP-1 R and transactivate the epidermal growth factor receptor (EGFR) via metalloproteinases

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Ognard J, El Hajj G, Ghozy S et al (2025) Quality of life in patients with spontaneous intracranial hypotension: A systematic review and meta-analysis
Potential health problems linked to these two drugs, as well as other GLP 1 drugs, include: Individuals who have used Wegovy and subsequently developed severe gastrointestinal issues, such as gastroparesis or intestinal blockages, may be eligible to file a lawsuit

President Trump last week hailed his deal with pharma companies to cut the price of blockbuster weight loss drugs as a major win for his administration and for increasing drug affordability
