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Description
GLP-2 acts through a G protein-coupled receptor GLP-2R

The genetic test reveals predispositionsnot predictions of exact medication response or hypoglycemia likelihood

This mechanism reduces appetite, slows gastric emptying, and enhances feelings of satiety, thereby supporting sustained weight loss when combined with a reduced-calorie diet and increased physical activity
Another two longer-acting analogs, glepaglutide and apraglutide, are currently undergoing phase III clinical trials

In fact, it is secreted by L-cells in the distal small intestine and colon in response to nutrient intake
