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In the landmark STEP 1 clinical trial, adults receiving 2.4 mg weekly semaglutide lost an average of 14.9% of their body weight over 68 weeks, compared with 2.4% in the placebo group (STEP 1 trial, New England Journal of Medicine , 2021)

The introduction of needle-free GLP-1 formulations addresses a critical access barrier, enabling treatment for patient populations who have been unable or unwilling to pursue injectable weight loss medications due to needle anxiety, lifestyle incompatibility, or administration preferences

Enhanced Distribution : CSF circulation helps distribute stem cells throughout the CNS, potentially reaching multiple sites of injury or disease

In the second half of the year, Amgen plans to release mid-stage trial data on an injectable drug that helped cause up to 14.5% weight loss after 12 weeks in an early study

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