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Reviews of formulation science confirm that newer delivery platforms can meaningfully improve solubility and bioavailability relative to native curcumin, although direct comparative clinical validation across systems including pharmacokinetic sub-studies embedded within metabolic trials remains incomplete (1, 8, 9)
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2008;36(Database issue):D901-6
However, it is rapidly degraded by the DPP-4 enzyme, giving it a one-two minute half-life
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