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Zepbound for weight management, subject to NICE guidance and local commissioning)

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Gastrointestinal Overlap: A Primary Concern Both Wegovy and Orlistat are well-known for their gastrointestinal side effects, which could be a significant concern if taken together: Wegovy (semaglutide) typically causes side effects such as nausea, vomiting, diarrhea, constipation, and abdominal pain