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It is also worth noting that SL did not end his fast due to intolerance or complication, but rather because his weight loss made him a candidate for bariatric surgery

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Early-stage data were striking: weekly injections produced about 22% weight loss over 36 weeks, while the oral form delivered around 13% over 12 weeks, in both cases without a clear plateau

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therefore, letrozole is considered first-line therapy

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