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Dan Ambinder, with mentorship from Dr

While this temporary slowdown in bowel motility is a known effect of how these medications work on your digestive system, constipation does not mean you must discontinue your GLP-1 therapy or reduce your dose

About the study Chefs prepared bone-in cuts consistently: Participants ate 200g bone-in Pirenaica beef or 150g boneless chicken per serving, cooked using standardized methods like grilling, stewing, or roasting across all study sites

Researchers are now investigating how VNS might interact with TGF- signaling, potentially fine-tuning its effects to improve metabolic health, while also focusing on the SPTBN1 protein, which acts as a switch for the TGF- system and may be a promising drug target

It likely reflects the threshold at which GLP-1 receptor activation becomes clinically significant, with the associated gastric motility changes that cause nausea