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Blood monocytes differentiate into several types of macrophages: classically activated types (M1) are pro-inflammatory and anti-fibrogenic, whereas alternatively activated M2 types are anti-inflammatory, pro-fibrogenic, and induce M1 cell apoptosis through IL-10 (Mosser and Edwards, 2008)

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A 12-week, double-blind, placebo-controlled trial published in Medicine found that red ginseng extract powder improved glycemic control in prediabetic Korean adults, with effects on blood glucose and insulin response consistent with incretin pathway involvement

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