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GLP-1 receptor agonist treatment improves fasting and postprandial lipidomic profiles independently of diabetes and weight loss

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Palmitic acid promotes human retinal pigment epithelial cells migration by upregulating miR-222 expression and inhibiting numb

This vascular impairment reduces nitric oxide availability, a critical molecule for smooth muscle relaxation and arterial dilation necessary for erection

Pharmacological inhibition or genetic reduction of DPP-4 activity preserves much higher circulating levels of intact GLP-1 [191,192], and this was demonstrated to potentiate the insulinotropic effect of GLP-1 in anesthetized pigs (eventually leading to the development of DPP-4 inhibitors for clinical use) [193]