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Liraglutide suppresses TNF--induced degradation of extracellular matrix in human chondrocytes: a therapeutic implication in osteoarthritis

doi: 10.1016/S0140-6736(20)32205-4 [DOI] [PMC free article] [PubMed] [Google Scholar] 5

Though newer GLP-1 analogs have taken center stage, DPP-4 inhibitors were the first incretin-based therapies that paved the way for todays metabolic revolution

Soykan I, Sarosiek I, McCallum RW

GLP-1RAs: Structure, Function, and Therapeutic Scope Molecular Basis: Endogenous GLP-1, Receptor Pharmacology, and Drug Engineering Endogenous GLP-1 is a 30amino-acid peptide generated by enzymatic processing of proglucagon in intestinal L-cells, pancreatic islet -cells, and neurons of the nucleus of the solitary tract [10, 18]