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Similarly, chitosan-modified PLGA NPs co-encapsulating liraglutide and alogliptin normalized glycemia for 24 h post-oral administration in STZ-induced diabetic rats, underscoring improved glucose regulation and the translational promise of non-invasive delivery routes [416]

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For patients with MASLD and preserved renal function who are prescribed metformin for diabetes management, clinicians should follow standard titration schedules while monitoring for gastrointestinal tolerability

The FDA, an agency within the U.S

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