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However, it does not replace testosterone therapy in men with primary hypogonadism

Regarding drug interactions, while semaglutide has few direct interactions affecting its elimination, patients should be aware of two important considerations: 1) Monitor INR more frequently when initiating semaglutide in patients taking warfarin, and 2) Increased levothyroxine exposure may occur with oral semaglutide (Rybelsus), requiring monitoring of thyroid function tests

The trial randomized and dosed 94 people for the first 12 weeks of study