is semaglutide a small molecule GLP-1 Genetics: How Genes Affect Appetite, Semaglutide, and Tirzepatide Response Binding sites and design strategies
Description
Tirzepatide is the first and only GLP-1 and glucose-dependent insulinotropic peptide (GIP) agonist approved by the FDA for the treatment of diabetes and obesity [11,12]
Effect sizes and reliability were reported
PMID: 45 TrujilloJ
It was suggested that this effect was due to reductions in TAG, since lipids are fuel for liver mass recovery
Patients with a history of diabetic retinopathy should be monitored for progression of diabetic retinopathy during treatment
