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For CDMOs, contract testing laboratories and other outsourced manufacturers, the implications are particularly significant the FDA considers contractors extensions of the manufacturer, meaning AI governance gaps at a contract facility can directly translate into compliance risk for the sponsor

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However, Ruminococcaceae usually acts as potential probiotics to ameliorate colitis, stressing more studies to clearly understand the effects of intestinal microflora in maintaining the intestinal epithelial layer integrity and the manifestation of UC