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Among the study participants treated with tirzepatide, 42.2% of those not using PAP therapy and 50.2% of those using PAP therapy achieved an AHI of fewer than five events per hour or between five and 14 events per hour, coupled with an Epworth Sleepiness Scale score of 10 or less, at the 52-week mark

The 30mg vial at this concentration provides 3mL of total solution, enough for multiple weeks of dosing without wasting reconstituted peptide before the 28-day expiration
Tirzepatide is administered once weekly by subcutaneous injection at any time of day, while metformin is taken daily with meals to reduce gastrointestinal side effects, with no specific timing coordination required between the two medications