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3 Jensen MD, Ryan DH, Apovian CM, et al

nearly a third of enrolled patients had stage 4 CKD (4)
It catches concentration mix-ups, arithmetic errors, syringe misreads, and dose escalation mistakes

Researchers running high-dose protocols that deplete vials quickly face less stability concern, but those on lower doses like 1mg or 2mg may find that a single vial lasts close to the stability window, making careful date tracking essential
doi: 10.1016/j.ygyno.2009.12.022
