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Hyperglycemia alters both extracellular and intracellular metabolism, leading to effects such as glomerular hyperfiltration (4), oxidative stress (5), the accumulation of advanced glycation end products (AGEs) (6), the activation of protein kinase C (7), abnormal polyol metabolism (8), the overexpression of transforming growth factor- (TGF-) (9) and inflammation

eGFR was calculated from the Chronic Kidney Disease Epidemiology Collaboration (CKDEPI) equation

Previous studies have highlighted the potential role of GLP-1R activation in modulating airway function

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Federal Lawyer Legal analysts project that total liability could exceed US $2 billion if many high-severity claims succeed