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This is mainly driven by a high prevalence of type 2 diabetes and obesity in the region

Gastrointestinal symptom profile: The most commonly reported adverse effects directly relate to delayed gastric motility

Future research should focus on mechanistic studies, long-term safety, and identifying biomarkers to predict dermatologic responses, ultimately guiding personalized treatment approaches

They stimulate insulin secretion, inhibit glucagon release, and slow gastric emptying, potentially exerting protective effects on renal function 13
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