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In March 2024 the FDA approved semaglutide to help to lower the risk of cardiovascular death, heart attack and stroke in overweight or obese patients (Patchen)

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Therefore, the main goal of treatment is not just to manage blood sugar levels but also to preserve kidney function, slow disease progression, and protect overall heart and vascular health

Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue
