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Description
The clinical development program established five dose tiers: 2.5mg, 5mg, 7.5mg, 10mg, and 15mg, administered once weekly via subcutaneous injection

doi:10.1161/CIRCULATIONAHA.119.041659 56
Extreme exposure: above 86 degrees Fahrenheit for any duration High heat is the deal-breaker

If morning injection consistently ruins your workday with nausea, switch to evening

Additionally, a high percentage of participants achieved a weight reduction of 5% or more (85% with 5 mg, 89% with 10 mg, and 91% with 15 mg of tirzepatide)
