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Modern lifestyle factorshigh-sugar, high-fat diets, sleep deprivation, and lack of physical activityfurther slow metabolism, making fat even harder to burn

Phase 2 trial results by dose (48 weeks) Phase 3 TRIUMPH-4 results (68 weeks) The phase 3 TRIUMPH-4 data, released in early 2026, confirmed and exceeded the phase 2 results
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The Treat and Reduce Obesity Act, HR4818, was introduced in 2023 with 65 cosponsors from across the aisle
