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Also, Zealand Pharma is developing long-acting amylin analogues for treatment of obesity and diabetes (142, 143)
Experimental and Clinical Endocrinology and Diabetes, 125 ,
Calorie restriction decreases murine and human pancreatic tumor cell growth, nuclear factor-B activation, and inflammation-related gene expression in an insulin-like growth factor-1-dependent manner
10.1038/nm.3009
They inhibit both COX-1 (associated with GI protection) and COX-2 (associated with inflammation)
