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These changes result from the direct effect of GLP-1RAs on proinflammatory cytokines production in monocytes/macrophages as it blocks NF-B, and lowers the formation of pro-inflammatory M1 macrophages
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Thyroid hormone receptor activation affects the expression of a wide range of genes, including metabolism and energy production.[ref] Recent research shows that mast cells have thyroid-stimulating hormone (TSH) receptors on their cell membranes
