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Shortly after starting tirzepatide in October, she noticed what she at first thought were signs of typical injection site irritation: some redness and itching

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In the second week, the subcutaneous injection of I-M-150847 (100nmol/kg) twice daily was continued but the control and treated mice were pair-fed for the entire second week and the body-weight gain and cumulative food intake was measured every day

Finally, we did a sensitivity analysis using an array approach to determine the necessary conditions for an unmeasured variable to substantially confound the observed association