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Medicare Begins Pilot Program for Low Cost GLP- 1s Millions of older Americans could soon pay less for popular GLP-1 weight-loss medications

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Semaglutide plus trevogrumab (myostatin inhibitor) preserves muscle mass in the setting of #weightloss over 26 weeks Regeneron #Weight 11.3% with combination vs 10.4% sema alone 4.2 lbs muscle with combination vs 7.9 lbs muscle with sema alone 18.9 lbs fat with combination vs 15.3 lbs fat with sema alone

SGLT-2i pairs, GLP-1RA therapy was associated with higher risks of HSV (HR=1.387, 95% CI=1.2491.539) and HZ (HR=1.294, 95% CI=1.2031.392) compared to DPP-4i and HSV (HR=1.277, 95% CI=1.1321.442) and HZ (HR=1.18, 95% CI=1.0851.284) compared to SGLT-2i