switching between glp-1 agonists chart Outcomes in RA-Experienced Patients to Once-Weekly Semaglutide in a Real-World Setting: The Retrospective, Observational EXPERT Study | Diabetes Therapy GLP-1 Agonists Market Report 2025-2033,

Summary Integrating emerging mechanistic and clinical observations, this review synthesizes current evidence from a metabolic flux perspective

A balanced microbiome environment can help support pathways involved in energy metabolism and appetite regulation

Gastroparesis and pulmonary aspiration risk GLP-1R agonists delay gastric emptying, leading to concerns about residual gastric content at the time of anaesthesia

### Competing Interest Statement ASK, AMM, MCG, JMD, CB, CL, SWB, DJL, PML, DRD, JMC, JPF, YL, ARS, DAT, DWP, SH, RBR, MSL, and DAG are employees and stockholders of Pfizer Inc

The global GLP-1 market is estimated to grow from USD 49.3 billion in the current year to USD 157