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51,113 Based on indications for the drug industry released by the FDA in 2019, candidate drugs achieving histological outcomes can be conditionally approved, and there remains a necessity to refine the assessment of clinical outcomes in the future

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The trial was not designed to investigate the mechanism of action of semaglutide on knee osteoarthritis, so mechanistic conclusions cannot be drawn

However, lifestyle-based weight loss strategies are not effective in the long term

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