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While SELECT demonstrated compelling outcomes, stakeholders will likely look for further evidence to substantiate the benefits of weight management with Wegovy outside the controlled setting of a clinical trial, e.g., in real world studies to confirm effectiveness and safety in routine medical practice when treating large numbers of patients of greater diversity, or via the SELECT-LIFE extension study, which invites SELECT patients to participate in a 10-year observational follow-up to evaluate long-term benefits

Overlooked research reveals a simple, cheap fix almost ignored.

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Unlike the well-known roles of GLP-1 and #PYY, the role of INSL5 is poorly understood, but this new research suggests it promotes colonic motility and in fact may be behind the cases of severe diarrhea (bile acid malabsorption in #IBS)

This article examines clinical safety, muscle preservation concerns, genetic predispositions to medication response, and how providers guide informed decision-making