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And theyre young, you know, theyre not like the normal 70-year-old you might see on the ward

For example, MRI scans were recently reinstated into a Phase 1 protocol due to the value of obtaining preliminary body composition data that could guide endpoint assessments for later pivotal trials

Rest/Stress myocardial perfusion imaging with PET has certain advantages over SPECT: Improved spatial resolution Ability to acquire stress images at peak stress if using dobutamine (versus lag time with SPECT) Absolute myocardial blood flow quantification with PET (not available with SPECT where perfusion is relative) With PET we can use either Rubidium-82 (half-life = 76 sec) or N-13 Ammonia (half-life = 10 min) as tracers to assess myocardial perfusion

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The findings indicated that patients on GLP-1RAs and/or DPP-4 inhibitors experienced better disease outcomes compared to those on different treatments, accompanied by an incidence rate ratio (IRR) of 0.52 (95% confidence interval: 0.420.65) [227]