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doi: 10.1016/j.redox.2017.04.019

HRT headaches may be related to hormone levels and require dose adjustment

Previous studies investigating the limitations of conventional AUD treatment highlight that the primary barrier to pharmacological efficacy is the need for intensive behavioral engagement, which has been frequently observed to hinder long-term adherence

On this basis, women are advised to avoid pregnancy until five half-lives of the drug have elapsed to allow adequate drug wash-out, and to advocate for trials that specifically include women planning pregnancy

Originally developed for type 2 diabetes management, several of these medications have received FDA approval for chronic weight management in adults with obesity (BMI 30) or overweight (BMI 27) with weight-related comorbidities