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Under this deal, Novo Nordisk has gained exclusive rights to develop and commercialize the drug outside of mainland China and its territories.

2 Department of Endocrinology, SANKO University Faculty of Medicine, Gaziantep, Turkey Correspondence: Nimet Ylmaz, Department of Gastroenterology, SANKO University Faculty of Medicine, Gaziantep, Turkey, Email [email protected] Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual GLP-1/GIP receptor agonists are highly effective agents for the treatment of type 2 diabetes and obesity

Retatrutide is administered as a once-weekly subcutaneous injection, typically into the abdomen, thigh, or upper arm

Extremely lowcalorie diets can raise lithogenic bile levels

Understanding how peptides work in the body provides additional context for these mechanisms