slow weight loss on tirzepatide reddit 3-year study maintenance results not as good as expected? : r/Zepbound Zepbound plateau: why weight loss

Serious hypoglycemia (blood glucose less than 54 mg/dL) in SURPASS-4 was reported less (9%) in individuals on tirzepatide than in individuals on insulin glargine (19%)

Pharmacologically, tirzepatide slows gastric emptying, which prolongs the sensation of fullness after eating, though this effect tends to diminish somewhat over time with continued treatment

Across all trials, 41 deaths occurred in individuals receiving tirzepatide ( n = 4573) and 39 in the comparator arms ( n = 2151)

Zepbound, also known generically as tirzepatide, and Ozempic, which includes semaglutide, fall under the incretin mimetics family of drugs, which copy a gut hormone that regulates multiple functions in the body

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