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The data offer early evidence that the injection can be administered less frequently than existing drugs without sacrificing efficacy, which could be a major boost for Pfizer after it faced several setbacks in developing obesity drugs

JAMA (2006) 295(13):154955.10.1001/jama.295.13.1549 2 KushnerRF

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These are based on animal studies only, where activation of GLP-1 receptors led to calcitonin release and C-cell hyperplasia
