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Recent comprehensive reviews of the many GLP-1 agonists that have come to the market in the last 20 years have been published elsewhere [8,37]

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These results are achieved alongside lifestyle measures, including a reduced-calorie diet (around 500 fewer calories per day) and at least 150 minutes of exercise per week

Some of the remaining undigested organic bone matrix is subsequently degraded by collagenases (especially histone K) (Lu et al., 2018)
