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In PWA groups, heatmaps displayed a clear separation between PWA + Vehicle and PWA + GLP1/E, indicating substantial alterations in proteomic profiles upon treatment, with both increased and decreased proteins being observed in the treated group (Fig

The resulting estimates of the Average Treatment Effect on the Treated (ATT) are presented with the 95% confidence interval (95% CI)

Semaglutide is one of several GLP-1 options

Together, these effects explain how GLP-1 controls appetite in a way that feels biologically natural rather than forced
