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ADA = American Diabetes Association, AUC = area under the curve, GDM = gestational diabetes mellitus, HbA1c = hemoglobin A1c, IS-SI = insulin secretion-sensitivity index, OGTT = oral glucose tolerance test, PET/CT = positron emission tomography/ computed tomography, P-glucose = plasma glucose, XR = extended release

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g , Top five most enriched functional terms for the 1518 differentially expressed genes that were downregulated following GLP-1MK-801 treatment relative to vehicle

GLP-1 and its therapeutic exploitation Glucagon-like peptide-1 (GLP-1) is a peptide hormone produced by specialised intestinal cells in response to food