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This evidence primarily comes from real-world data on the use of semaglutide and tirzepatide in T1D patients with concomitant overweight/obesity, although a randomized crossover trial investigating the efficacy of semaglutide in adults with T1D using an automated insulin delivery system has recently been published (discussed later in the manuscript)

Researchers who have studied AOD 9604 dosage protocols generally recommend morning administration before food intake for this reason

Bioavailability refers to the percentage of a medication that successfully enters the bloodstream to perform its job
