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Orforglipron is under regulatory review for weight loss and Type 2 diabetes

Thus, in addition to a comprehensive approach encompassing multidisciplinary risk factors (dyslipidaemia, hypertension, obesity, smoking, etc.) [8, 9], considering "what drugs to use to lower blood glucose" by selecting hypoglycaemic agents with evidence-based cardiorenal protective effects, according to patient background and risk status is increasingly important [10]

Many people with obesity are at risk for other health conditions, like heart disease, stroke, liver disease, and kidney disease

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[DOI] [PubMed] [Google Scholar] 84.Trujillo J.M., Nuffer W., Smith B.A