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This dual activation produces stronger appetite suppression, greater weight loss, and improved metabolic markers compared to GLP-1-only medications in head-to-head clinical trials

Rapid blood pressure drops are rare but can occur in patients already on multiple blood pressure medicationsanother reason close monitoring during the first month is essential

Your healthcare team can help guide you through the transition process

Authors are thankful for the support provided by the NIH grants R01HL142930 (KK) and R01HL132035 (XZ), a grant from the Pepper Older Americans for Independence Center (P30AG21332), and grants from the Department of Defense funding W81XWH-18-1-0118, W81XWH-19-1-0236, and R01AG018915 (HY), as well funds and services provided from the Center for Diabetes, Obesity and Metabolism, Wake Forest Baptist Medical Center, and the National Center for Advancing Translational Sciences (NCATS)

Their role may include: Using a GLP-1 medication safely while caring for your relationship with food is possible with coordinated support