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Any plasma samples found to have analyte concentrations above the upper limit of quantification (ULOQ) were diluted by a factor of 4, 5, 10, or 20, as appropriate, to bring the concentration within the quantifiable range

Some clinicians and researchers explore split semaglutide dosing twice weekly or split tirzepatide dosing as a way to maintain more consistent blood levels and potentially improve results while reducing peak-dose side effects

Tirzepatide carries similar considerations

As a reminder, agonists attempt to mimic the molecules action, while antagonists attempt to block the molecules action

Tirzepatide helps with weight loss by: Reducing appetite and cravings Improving fullness after meals Stabilizing blood sugar Supporting healthier insulin responses What about its effects on fat cells