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When tirzepatide activates GLP-1 receptors, it enhances glucose-dependent insulin secretion from pancreatic beta cells, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying

Your starting weight, metabolism, insulin resistance, eating habits, activity level, genetics, and treatment goals all influence which dose works best for you

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M., et al., Tirzepatide for Heart Failure With Preserved Ejection Fraction and Obesity, New England Journal of Medicine 392, no
